Antigen Receptor–Induced Activation and Cytoskeletal Rearrangement Are Impaired in Wiskott-Aldrich Syndrome Protein–Deficient Lymphocytes

The Wiskott-Aldrich syndrome protein (WASp) has been implicated in modulation of lymphocyte activation and cytoskeletal reorganization. To address the mechanisms whereby WASp subserves such functions, we have examined WASp roles in lymphocyte development and activation using mice carrying a WAS null...

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Detalles Bibliográficos
Autores principales: Zhang, Jinyi, Shehabeldin, Amro, da Cruz, Luis A.G., Butler, Jeffrey, Somani, Ally-Khan, McGavin, Mary, Kozieradzki, Ivona, dos Santos, Antonio O., Nagy, Andras, Grinstein, Sergio, Penninger, Josef M., Siminovitch, Katherine A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195687/
https://www.ncbi.nlm.nih.gov/pubmed/10544204

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