Association of the Adaptor Molecule Lat with Cd4 and Cd8 Coreceptors Identifies a New Coreceptor Function in T Cell Receptor Signal Transduction

Linker for activation of T cells (LAT) is an adaptor protein whose tyrosine phosphorylation is critical for transduction of the T cell receptor (TCR) signal. LAT phosphorylation is accomplished by the protein tyrosine kinase ZAP-70, but it is not at all clear how LAT (which is not associated with th...

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Detalles Bibliográficos
Autores principales: Bosselut, Rémy, Zhang, Weiguo, Ashe, Jennifer M., Kopacz, Jeffrey L., Samelson, Lawrence E., Singer, Alfred
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195704/
https://www.ncbi.nlm.nih.gov/pubmed/10562325

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