Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Required for P-Selectin–Mediated but Not E-Selectin–Mediated Neutrophil Rolling and Migration

P-selectin glycoprotein ligand 1 (PSGL-1) is a mucin-like selectin counterreceptor that binds to P-selectin, E-selectin, and L-selectin. To determine its physiological role in cell adhesion as a mediator of leukocyte rolling and migration during inflammation, we prepared mice genetically deficient i...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jing, Hirata, Takako, Croce, Kevin, Merrill-Skoloff, Glenn, Tchernychev, Boris, Williams, Eric, Flaumenhaft, Robert, Furie, Barbara C., Furie, Bruce
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195714/
https://www.ncbi.nlm.nih.gov/pubmed/10601352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195714/
https://www.ncbi.nlm.nih.gov/pubmed/10601352

Ejemplares similares