Extracellular Signal–Regulated Kinase (Erk) Activation by the Pre-T Cell Receptor in Developing Thymocytes in Vivo

The first checkpoint in T cell development occurs between the CD4(−)CD8(−) and CD4(+)CD8(+) stages and is associated with formation of the pre-T cell receptor (TCR). The signaling mechanisms that drive this progression remain largely unknown. Here, we show that extracellular signal–regulated kinases...

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Detalles Bibliográficos
Autores principales: Michie, Alison M., Trop, Sébastien, Wiest, David L., Zúñiga-Pflücker, Juan Carlos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195734/
https://www.ncbi.nlm.nih.gov/pubmed/10587355

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