Thymocyte Maturation Is Regulated by the Activity of the Helix-Loop-Helix Protein, E47

The E2A proteins, E12 and E47, are required for progression through multiple developmental pathways, including early B and T lymphopoiesis. Here, we provide in vitro and in vivo evidence demonstrating that E47 activity regulates double-positive thymocyte maturation. In the absence of E47 activity, p...

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Detalles Bibliográficos
Autores principales: Bain, Gretchen, Quong, Melanie W., Soloff, Rachel S., Hedrick, Stephen M., Murre, Cornelis
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195738/
https://www.ncbi.nlm.nih.gov/pubmed/10587351

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