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Cytotoxic T Lymphocyte Epitopes of HIV-1 Nef: Generation of Multiple Definitive Major Histocompatibility Complex Class I Ligands by Proteasomes
Although a pivotal role of proteasomes in the proteolytic generation of epitopes for major histocompatibility complex (MHC) class I presentation is undisputed, their precise function is currently the subject of an active debate: do proteasomes generate many epitopes in definitive form, or do they me...
Autores principales: | Lucchiari-Hartz, Maria, van Endert, Peter M., Lauvau, Grégoire, Maier, Reinhard, Meyerhans, Andreas, Mann, Derek, Eichmann, Klaus, Niedermann, Gabriele |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195755/ https://www.ncbi.nlm.nih.gov/pubmed/10637269 |
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