Hsp70 and Antifibrillogenic Peptides Promote Degradation and Inhibit Intracellular Aggregation of Amyloidogenic Light Chains

In light chain (LC) amyloidosis an immunoglobulin LC assembles into fibrils that are deposited in various tissues. Little is known about how these fibrils form in vivo. We previously showed that a known amyloidogenic LC, SMA, can give rise to amyloid fibrils in vitro when a segment of one of its β s...

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Detalles Bibliográficos
Autores principales: Dul, Jeanne L., Davis, David P., Williamson, Edward K., Stevens, Fred J., Argon, Yair
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195780/
https://www.ncbi.nlm.nih.gov/pubmed/11266462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195780/
https://www.ncbi.nlm.nih.gov/pubmed/11266462

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