Presenilin 1 Negatively Regulates β-Catenin/T Cell Factor/Lymphoid Enhancer Factor-1 Signaling Independently of β-Amyloid Precursor Protein and Notch Processing

In addition to its documented role in the proteolytic processing of Notch-1 and the β-amyloid precursor protein, presenilin 1 (PS1) associates with β-catenin. In this study, we show that this interaction plays a critical role in regulating β-catenin/T Cell Factor/Lymphoid Enhancer Factor-1 (LEF) sig...

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Detalles Bibliográficos
Autores principales: Soriano, Salvador, Kang, David E., Fu, Maofu, Pestell, Richard, Chevallier, Nathalie, Zheng, Hui, Koo, Edward H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195782/
https://www.ncbi.nlm.nih.gov/pubmed/11266469

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