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Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells
In macroautophagy, cytoplasmic components are delivered to lysosomes for degradation via autophagosomes that are formed by closure of cup-shaped isolation membranes. However, how the isolation membranes are formed is poorly understood. We recently found in yeast that a novel ubiquitin-like system, t...
Autores principales: | Mizushima, Noboru, Yamamoto, Akitsugu, Hatano, Masahiko, Kobayashi, Yoshinori, Kabeya, Yukiko, Suzuki, Kuninori, Tokuhisa, Takeshi, Ohsumi, Yoshinori, Yoshimori, Tamotsu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195787/ https://www.ncbi.nlm.nih.gov/pubmed/11266458 |
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