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In Vivo Evidence for the Contribution of Human Histocompatibility Leukocyte Antigen (Hla)-Dq Molecules to the Development of Diabetes
Although DQA1*0301/DQB1*0302 is the human histocompatibility leukocyte antigen (HLA) class II gene most commonly associated with human type 1 diabetes, direct in vivo experimental evidence for its diabetogenic role is lacking. Therefore, we generated C57BL/6 transgenic mice that bear this molecule a...
Autores principales: | Wen, Li, Wong, F. Susan, Tang, Jie, Chen, Ning-Yuan, Altieri, Martha, David, Chella, Flavell, Richard, Sherwin, Robert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195792/ https://www.ncbi.nlm.nih.gov/pubmed/10620608 |
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