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Tumor Necrosis Factor Sustains the Generalized Lymphoproliferative Disorder ( gld ) Phenotype

Tumor necrosis factor (TNF) and Fas ligand (FasL) play major roles in the homeostasis of the peripheral immune system. This becomes dramatically obvious in the absence of a functional FasL. Mice with such a deficiency develop a profound lymphadenopathy, splenomegaly, hypergammaglobulinemia, and stra...

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Detalles Bibliográficos
Autores principales: Körner, Heinrich, Cretney, Erika, Wilhelm, Patricia, Kelly, Janice M., Röllinghoff, Martin, Sedgwick, Jonathon D., Smyth, Mark J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195803/
https://www.ncbi.nlm.nih.gov/pubmed/10620607