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Tumor Necrosis Factor Sustains the Generalized Lymphoproliferative Disorder ( gld ) Phenotype
Tumor necrosis factor (TNF) and Fas ligand (FasL) play major roles in the homeostasis of the peripheral immune system. This becomes dramatically obvious in the absence of a functional FasL. Mice with such a deficiency develop a profound lymphadenopathy, splenomegaly, hypergammaglobulinemia, and stra...
Autores principales: | Körner, Heinrich, Cretney, Erika, Wilhelm, Patricia, Kelly, Janice M., Röllinghoff, Martin, Sedgwick, Jonathon D., Smyth, Mark J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195803/ https://www.ncbi.nlm.nih.gov/pubmed/10620607 |
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