bcl-2 Transgene Expression Inhibits Apoptosis in the Germinal Center and Reveals Differences in the Selection of Memory B Cells and Bone Marrow Antibody-Forming Cells

Immunization with T cell–dependent antigens generates long-lived memory B cells and antibody-forming cells (AFCs). Both populations originate in germinal centers and, predominantly, produce antibodies with high affinity for antigen. The means by which germinal center B cells are recruited into these...

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Detalles Bibliográficos
Autores principales: Smith, Kenneth G.C., Light, Amanda, O'Reilly, Lorraine A., Ang, Soon-Meng, Strasser, Andreas, Tarlinton, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195819/
https://www.ncbi.nlm.nih.gov/pubmed/10662793

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