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Germinal Centers without T Cells

Germinal centers are critical for affinity maturation of antibody (Ab) responses. This process allows the production of high-efficiency neutralizing Ab that protects against virus infection and bacterial exotoxins. In germinal centers, responding B cells selectively mutate the genes that encode thei...

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Detalles Bibliográficos
Autores principales: de Vinuesa, Carola García, Cook, Matthew C., Ball, Jennifer, Drew, Marion, Sunners, Yvonne, Cascalho, Marilia, Wabl, Matthias, Klaus, Gerry G.B., MacLennan, Ian C.M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195827/
https://www.ncbi.nlm.nih.gov/pubmed/10662794