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The Intestinal T Cell Response to α-Gliadin in Adult Celiac Disease Is Focused on a Single Deamidated Glutamine Targeted by Tissue Transglutaminase
The great majority of patients that are intolerant of wheat gluten protein due to celiac disease (CD) are human histocompatibility leukocyte antigen (HLA)-DQ2(+), and the remaining few normally express HLA-DQ8. These two class II molecules are chiefly responsible for the presentation of gluten pepti...
Autores principales: | Arentz-Hansen, Helene, Körner, Roman, Molberg, Øyvind, Quarsten, Hanne, Vader, Willemijn, Kooy, Yvonne M.C., Lundin, Knut E.A., Koning, Frits, Roepstorff, Peter, Sollid, Ludvig M., McAdam, Stephen N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195837/ https://www.ncbi.nlm.nih.gov/pubmed/10684852 |
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