Induction and Suppression of an Autoimmune Disease by Oligomerized T Cell Epitopes: Enhanced in Vivo Potency of Encephalitogenic Peptides

T cell epitope peptides derived from proteolipid protein (PLP139–151) or myelin basic protein (MBP86–100) induce experimental autoimmune encephalomyelitis (EAE) in “susceptible” strains of mice (e.g., SJL/J). In this study, we show that the encephalitogenic effect of these epitopes when injected sub...

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Detalles Bibliográficos
Autores principales: Falk, Kirsten, Rötzschke, Olaf, Santambrogio, Laura, Dorf, Martin E., Brosnan, Celia, Strominger, Jack L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195838/
https://www.ncbi.nlm.nih.gov/pubmed/10684863

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