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Identification of Ny-Eso-1 Epitopes Presented by Human Histocompatibility Antigen (Hla)-Drb4*0101–0103 and Recognized by Cd4(+)T Lymphocytes of Patients with Ny-Eso-1–Expressing Melanoma
NY-ESO-1 is a member of the cancer-testis family of tumor antigens that elicits strong humoral and cellular immune responses in patients with NY-ESO-1–expressing cancers. Since CD4(+) T lymphocytes play a critical role in generating antigen-specific cytotoxic T lymphocyte and antibody responses, we...
Autores principales: | Jäger, Elke, Jäger, Dirk, Karbach, Julia, Chen, Yao-Tseng, Ritter, Gerd, Nagata, Yasuhiro, Gnjatic, Sacha, Stockert, Elisabeth, Arand, Michael, Old, Lloyd J., Knuth, Alexander |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195843/ https://www.ncbi.nlm.nih.gov/pubmed/10684854 |
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