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Mapping the Energy of Superantigen Staphylococcus Enterotoxin C3 Recognition of an α/β T Cell Receptor Using Alanine Scanning Mutagenesis
Binding of the T cell receptor (TCR) to a bacterial superantigen (SAG) results in stimulation of a large population of T cells and subsequent inflammatory reactions. To define the functional contribution of TCR residues to SAG recognition, binding by 24 single-site alanine substitutions in the TCR V...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2000
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195847/ https://www.ncbi.nlm.nih.gov/pubmed/10704464 |