Immunotherapy with Dendritic Cells Directed against Tumor Antigens Shared with Normal Host Cells Results in Severe Autoimmune Disease

Vaccination with dendritic cells (DCs) presenting tumor antigens induces primary immune response or amplifies existing cytotoxic antitumor T cell responses. This study documents that antitumor treatment with DCs may cause severe autoimmune disease when the tumor antigens are not tumor-specific but a...

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Detalles Bibliográficos
Autores principales: Ludewig, Burkhard, Ochsenbein, Adrian F., Odermatt, Bernhard, Paulin, Denise, Hengartner, Hans, Zinkernagel, Rolf M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195849/
https://www.ncbi.nlm.nih.gov/pubmed/10704461

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