Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice

C57BL/6 mice genetically deficient in interleukin 15 (IL-15(−/−) mice) were generated by gene targeting. IL-15(−/−) mice displayed marked reductions in numbers of thymic and peripheral natural killer (NK) T cells, memory phenotype CD8(+) T cells, and distinct subpopulations of intestinal intraepithe...

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Detalles Bibliográficos
Autores principales: Kennedy, Mary K., Glaccum, Moira, Brown, Sandra N., Butz, Eric A., Viney, Joanne L., Embers, Monica, Matsuki, Naoto, Charrier, Keith, Sedger, Lisa, Willis, Cynthia R., Brasel, Kenneth, Morrissey, Philip J., Stocking, Kim, Schuh, JoAnn C. L., Joyce, Sebastian, Peschon, Jacques J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195858/
https://www.ncbi.nlm.nih.gov/pubmed/10704459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195858/
https://www.ncbi.nlm.nih.gov/pubmed/10704459

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