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Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice
C57BL/6 mice genetically deficient in interleukin 15 (IL-15(−/−) mice) were generated by gene targeting. IL-15(−/−) mice displayed marked reductions in numbers of thymic and peripheral natural killer (NK) T cells, memory phenotype CD8(+) T cells, and distinct subpopulations of intestinal intraepithe...
Autores principales: | Kennedy, Mary K., Glaccum, Moira, Brown, Sandra N., Butz, Eric A., Viney, Joanne L., Embers, Monica, Matsuki, Naoto, Charrier, Keith, Sedger, Lisa, Willis, Cynthia R., Brasel, Kenneth, Morrissey, Philip J., Stocking, Kim, Schuh, JoAnn C. L., Joyce, Sebastian, Peschon, Jacques J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195858/ https://www.ncbi.nlm.nih.gov/pubmed/10704459 |
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