Transient Inhibition of Interleukin 4 Signaling by T Cell Receptor Ligation

Interleukin (IL)-4 and IL-12 together with T cell receptor (TCR) engagement are crucial for the differentiation of CD4(+) T cells into T helper (Th)2 or Th1 cells, respectively. Although IL-4 receptors (IL-4Rs) but not IL-12Rs are expressed on naive CD4(+) T cells, IL-4 has no apparent advantage ove...

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Detalles Bibliográficos
Autores principales: Zhu, Jinfang, Huang, Hua, Guo, Liying, Stonehouse, Timothy, Watson, Cynthia J., Hu-Li, Jane, Paul, William E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195871/
https://www.ncbi.nlm.nih.gov/pubmed/11034602

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