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Iκb Kinase α Is Essential for Mature B Cell Development and Function
IκB kinase (IKK) α and β phosphorylate IκB proteins and activate the transcription factor, nuclear factor (NF)-κB. Although both are highly homologous kinases, gene targeting experiments revealed their differential roles in vivo. IKKα is involved in skin and limb morphogenesis, whereas IKKβ is essen...
Autores principales: | Kaisho, Tsuneyasu, Takeda, Kiyoshi, Tsujimura, Tohru, Kawai, Taro, Nomura, Fumiko, Terada, Nobuyuki, Akira, Shizuo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195900/ https://www.ncbi.nlm.nih.gov/pubmed/11181694 |
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