Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2

Viral protein R (Vpr), an apoptogenic accessory protein encoded by HIV-1, induces mitochondrial membrane permeabilization (MMP) via a specific interaction with the permeability transition pore complex, which comprises the voltage-dependent anion channel (VDAC) in the outer membrane (OM) and the aden...

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Detalles Bibliográficos
Autores principales: Jacotot, Etienne, Ferri, Karine F., El Hamel, Chahrazed, Brenner, Catherine, Druillennec, Sabine, Hoebeke, Johan, Rustin, Pierre, Métivier, Didier, Lenoir, Christine, Geuskens, Maurice, Vieira, Helena L.A., Loeffler, Markus, Belzacq, Anne-Sophie, Briand, Jean-Paul, Zamzami, Naoufal, Edelman, Lena, Xie, Zhi Hua, Reed, John C., Roques, Bernard P., Kroemer, Guido
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195906/
https://www.ncbi.nlm.nih.gov/pubmed/11181702

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