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Enhancement of Osteoclastic Bone Resorption and Suppression of Osteoblastic Bone Formation in Response to Reduced Mechanical Stress Do Not Occur in the Absence of Osteopontin
Reduced mechanical stress to bone in bedridden patients and astronauts leads to bone loss and increase in fracture risk which is one of the major medical and health issues in modern aging society and space medicine. However, no molecule involved in the mechanisms underlying this phenomenon has been...
Autores principales: | Ishijima, Muneaki, Rittling, Susan R., Yamashita, Teruhito, Tsuji, Kunikazu, Kurosawa, Hisashi, Nifuji, Akira, Denhardt, David T., Noda, Masaki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195919/ https://www.ncbi.nlm.nih.gov/pubmed/11157060 |
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