Fes-Cre Targets Phosphatidylinositol Glycan Class a (Piga) Inactivation to Hematopoietic Stem Cells in the Bone Marrow

A somatic mutation in the X-linked phosphatidylinositol glycan class A (PIGA) gene causes the loss of glycosyl phosphatidylinositol (GPI)-linked proteins on blood cells from patients with paroxysmal nocturnal hemoglobinuria. Because all blood cell lineages may be affected it is thought that the muta...

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Detalles Bibliográficos
Autores principales: Keller, Peter, Payne, Jennifer L., Tremml, Gabi, Greer, Peter A., Gaboli, Mirella, Pandolfi, Pier P., Bessler, Monica
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195941/
https://www.ncbi.nlm.nih.gov/pubmed/11535627

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