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A Pathogenic Role for Myelin-Specific Cd8(+) T Cells in a Model for Multiple Sclerosis
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) characterized by plaques of infiltrating CD4(+) and CD8(+) T cells. Studies of MS and experimental autoimmune encephalomyelitis (EAE), an animal model of MS, focus on the contribution of CD4(+) myelin-specific T c...
Autores principales: | Huseby, Eric S., Liggitt, Denny, Brabb, Thea, Schnabel, Bryan, Öhlén, Claes, Goverman, Joan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195947/ https://www.ncbi.nlm.nih.gov/pubmed/11535634 |
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