Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β(1)

Interleukin (IL)-13 is a key mediator of tissue fibrosis caused by T helper cell type 2 inflammation. We hypothesized that the fibrogenic effects of IL-13 are mediated by transforming growth factor (TGF)-β. To test this hypothesis we compared the regulation of TGF-β in lungs from wild-type mice and...

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Detalles Bibliográficos
Autores principales: Lee, Chun Geun, Homer, Robert J., Zhu, Zhou, Lanone, Sophie, Wang, Xiaoman, Koteliansky, Victor, Shipley, J. Michael, Gotwals, Philip, Noble, Paul, Chen, Qingsheng, Senior, Robert M., Elias, Jack A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195954/
https://www.ncbi.nlm.nih.gov/pubmed/11560996

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