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B7H Costimulates Clonal Expansion of, and Cognate Destruction of Tumor Cells by, CD8(+) T Lymphocytes In Vivo

B7H/B7RP (hereby called B7H) is a new member of the B7 family of costimulatory molecules and interacts with inducible costimulatory molecule (ICOS). Its function for CD8 T cells has not been reported. We report here that expression of B7H on the tumor cells reduced tumorigenicity and induced immunit...

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Detalles Bibliográficos
Autores principales: Liu, Xingluo, Bai, Xue-Feng, Wen, Jing, Gao, Jian-Xin, Liu, Jinqing, Lu, Ping, Wang, Yin, Zheng, Pan, Liu, Yang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195972/
https://www.ncbi.nlm.nih.gov/pubmed/11696598