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Functional Cloning of Src-like Adapter Protein-2 (SLAP-2), a Novel Inhibitor of Antigen Receptor Signaling

In an effort to identify novel therapeutic targets for autoimmunity and transplant rejection, we developed and performed a large-scale retroviral-based functional screen to select for proteins that inhibit antigen receptor-mediated activation of lymphocytes. In addition to known regulators of antige...

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Detalles Bibliográficos
Autores principales: Holland, Sacha J., Liao, X. Charlene, Mendenhall, Marcy K., Zhou, Xiulan, Pardo, Jorge, Chu, Peter, Spencer, Collin, Fu, Alan, Sheng, Ning, Yu, Peiwen, Pali, Erlina, Nagin, Anup, Shen, Mary, Yu, Simon, Chan, Eva, Wu, Xian, Li, Connie, Woisetschlager, Max, Aversa, Gregorio, Kolbinger, Frank, Bennett, Mark K., Molineaux, Susan, Luo, Ying, Payan, Donald G., Mancebo, Helena S.Y., Wu, Jun
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195979/
https://www.ncbi.nlm.nih.gov/pubmed/11696592

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