Cargando…
Dominant-Interfering Hsc70 Mutants Disrupt Multiple Stages of the Clathrin-Coated Vesicle Cycle in Vivo
Within the clathrin-coated vesicle (CCV) cycle, coat assembly drives the internalization of receptors from the cell surface and disassembly allows for the processing of internalized ligands. The heat shock cognate protein, hsc70, has been implicated in regulating coat disassembly. We find that in ce...
Autores principales: | Newmyer, Sherri L., Schmid, Sandra L. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196005/ https://www.ncbi.nlm.nih.gov/pubmed/11157986 |
Ejemplares similares
-
Hsc70 is required for endocytosis and clathrin function in Drosophila
por: Chang, Henry C., et al.
Publicado: (2002) -
Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly
por: Xing, Yi, et al.
Publicado: (2010) -
Hsc70-induced Changes in Clathrin-Auxilin Cage Structure Suggest a Role for Clathrin Light Chains in Cage Disassembly
por: Young, Anna, et al.
Publicado: (2013) -
Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles
por: Kovtun, Oleksiy, et al.
Publicado: (2020) -
The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila
por: Chang, Henry C., et al.
Publicado: (2004)