Antitumor Monoclonal Antibodies Enhance Cross-Presentation of Cellular Antigens and the Generation of Myeloma-specific Killer T Cells by Dendritic Cells

The mechanism of antitumor effect of monoclonal antibodies (mAbs) is not fully understood. Here we show that coating myeloma cells with anti–syndecan-1 antibody promotes cross-presentation of cellular antigens by dendritic cells (DCs) to autologous T cells from healthy donors. The tumor cells treate...

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Detalles Bibliográficos
Autores principales: Dhodapkar, Kavita M., Krasovsky, Joseph, Williamson, Barbara, Dhodapkar, Madhav V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196013/
https://www.ncbi.nlm.nih.gov/pubmed/11781371
http://dx.doi.org/10.1084/jem.20011097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196013/
https://www.ncbi.nlm.nih.gov/pubmed/11781371
http://dx.doi.org/10.1084/jem.20011097

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