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T Helper 1 and T Helper 2 Cells Are Pathogenic in an Antigen-specific Model of Colitis

Dysregulated T cell responses to enteric bacteria have been implicated as a common mechanism underlying pathogenesis in rodent models of colitis. However, the bacterial species and T cell specificities that induce disease have been poorly defined. We have developed a model system in which target ant...

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Detalles Bibliográficos
Autores principales: Iqbal, Nuzhat, Oliver, James R., Wagner, Frederic H., Lazenby, Audrey S., Elson, Charles O., Weaver, Casey T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196021/
https://www.ncbi.nlm.nih.gov/pubmed/11781367
http://dx.doi.org/10.1084/jem.2001889