Cytokine Response Modifier A (CrmA) Inhibits Ceramide Formation in Response to Tumor Necrosis Factor (TNF)-α: CrmA and Bcl-2 Target Distinct Components in the Apoptotic Pathway

Proteases are now firmly established as major regulators of the “execution” phase of apoptosis. Here, we examine the role of proteases and their relationship to ceramide, a proposed mediator of apoptosis, in the tumor necrosis factor-α (TNF-α)–induced pathway of cell death. Ceramide induced activati...

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Detalles Bibliográficos
Autores principales: Dbaibo, Ghassan S., Perry, David K., Gamard, Chris J., Platt, Rheanna, Poirier, Guy G., Obeid, Lina M., Hannun, Yusuf A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196031/
https://www.ncbi.nlm.nih.gov/pubmed/9053448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196031/
https://www.ncbi.nlm.nih.gov/pubmed/9053448

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