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Interleukin (IL)-6 Directs the Differentiation of IL-4–producing CD4(+) T Cells
Interleukin (IL)-4 is the most potent factor that causes naive CD4(+) T cells to differentiate to the T helper cell (Th) 2 phenotype, while IL-12 and interferon γ trigger the differentiation of Th1 cells. However, the source of the initial polarizing IL-4 remains unclear. Here, we show that IL-6, pr...
Autores principales: | Rincón, Mercedes, Anguita, Juan, Nakamura, Tetsuo, Fikrig, Erol, Flavell, Richard A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196041/ https://www.ncbi.nlm.nih.gov/pubmed/9053446 |
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