Surface Cathepsin B Protects Cytotoxic Lymphocytes from Self-destruction after Degranulation

The granule exocytosis cytotoxicity pathway is the major molecular mechanism for cytotoxic T lymphocyte (CTL) and natural killer (NK) cytotoxicity, but the question of how these cytotoxic lymphocytes avoid self-destruction after secreting perforin has remained unresolved. We show that CTL and NK cel...

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Detalles Bibliográficos
Autores principales: Balaji, Kithiganahalli N., Schaschke, Norbert, Machleidt, Werner, Catalfamo, Marta, Henkart, Pierre A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196055/
https://www.ncbi.nlm.nih.gov/pubmed/12186841
http://dx.doi.org/10.1084/jem.20011836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196055/
https://www.ncbi.nlm.nih.gov/pubmed/12186841
http://dx.doi.org/10.1084/jem.20011836

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