Inhibition of Allogeneic T Cell Proliferation by Indoleamine 2,3-Dioxygenase–expressing Dendritic Cells: Mediation of Suppression by Tryptophan Metabolites

Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the catabolism of tryptophan, is expressed in certain cells and tissues, particularly in antigen-presenting cells of lymphoid organs and in the placenta. It was shown that IDO prevents rejection of the fetus during pregnancy, probably by inhib...

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Detalles Bibliográficos
Autores principales: Terness, Peter, Bauer, Thomas M., Röse, Lars, Dufter, Christoph, Watzlik, Andrea, Simon, Helmut, Opelz, Gerhard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196057/
https://www.ncbi.nlm.nih.gov/pubmed/12186837
http://dx.doi.org/10.1084/jem.20020052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196057/
https://www.ncbi.nlm.nih.gov/pubmed/12186837
http://dx.doi.org/10.1084/jem.20020052

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