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CD4(+) T Cells from Glutamic Acid Decarboxylase (GAD)65-specific T Cell Receptor Transgenic Mice Are Not Diabetogenic and Can Delay Diabetes Transfer

Glutamic acid decarboxylase (GAD)65 is an early and important antigen in both human diabetes mellitus and the nonobese diabetic (NOD) mouse. However, the exact role of GAD65-specific T cells in diabetes pathogenesis is unclear. T cell responses to GAD65 occur early in diabetes pathogenesis, yet only...

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Detalles Bibliográficos
Autores principales:	Tarbell, Kristin V., Lee, Mark, Ranheim, Erik, Chao, Cheng Chi, Sanna, Maija, Kim, Seon-Kyeong, Dickie, Peter, Teyton, Luc, Davis, Mark, McDevitt, Hugh
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196059/ https://www.ncbi.nlm.nih.gov/pubmed/12186840 http://dx.doi.org/10.1084/jem.20011845

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