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The PAAD/PYRIN-Family Protein ASC Is a Dual Regulator of a Conserved Step in Nuclear Factor κB Activation Pathways

Apoptosis-associated speck-like protein containing a Caspase recruitment domain (ASC) belongs to a large family of proteins that contain a Pyrin, AIM, ASC, and death domain-like (PAAD) domain (also known as PYRIN, DAPIN, Pyk). Recent data have suggested that ASC functions as an adaptor protein linki...

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Detalles Bibliográficos
Autores principales: Stehlik, Christian, Fiorentino, Loredana, Dorfleutner, Andrea, Bruey, Jean-Marie, Ariza, Eugenia M., Sagara, Junji, Reed, John C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196065/
https://www.ncbi.nlm.nih.gov/pubmed/12486103
http://dx.doi.org/10.1084/jem.20021552