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The PAAD/PYRIN-Family Protein ASC Is a Dual Regulator of a Conserved Step in Nuclear Factor κB Activation Pathways
Apoptosis-associated speck-like protein containing a Caspase recruitment domain (ASC) belongs to a large family of proteins that contain a Pyrin, AIM, ASC, and death domain-like (PAAD) domain (also known as PYRIN, DAPIN, Pyk). Recent data have suggested that ASC functions as an adaptor protein linki...
Autores principales: | Stehlik, Christian, Fiorentino, Loredana, Dorfleutner, Andrea, Bruey, Jean-Marie, Ariza, Eugenia M., Sagara, Junji, Reed, John C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196065/ https://www.ncbi.nlm.nih.gov/pubmed/12486103 http://dx.doi.org/10.1084/jem.20021552 |
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