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Cross-presentation of Disialoganglioside GD3 to Natural Killer T Cells
GD3, a ganglioside expressed on human melanoma, can be recognized by the humoral immune system. In this paper, we demonstrate that immunizing mice with the human melanoma cell line SK-MEL-28 (GD3(+) GM2(−) CD1(−)) or with syngeneic APCs loaded with GD3 can induce a GD3-reactive natural killer T (NKT...
Autores principales: | Wu, Dianna Y., Segal, Neil H., Sidobre, Stephane, Kronenberg, Mitchell, Chapman, Paul B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196074/ https://www.ncbi.nlm.nih.gov/pubmed/12847141 http://dx.doi.org/10.1084/jem.20030446 |
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