The Runx1 Transcription Factor Inhibits the Differentiation of Naive CD4(+) T Cells into the Th2 Lineage by Repressing GATA3 Expression

Differentiation of naive CD4(+) T cells into helper T (Th) cells is controlled by a combination of several transcriptional factors. In this study, we examined the functional role of the Runx1 transcription factor in Th cell differentiation. Naive T cells from transgenic mice expressing a dominant in...

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Detalles Bibliográficos
Autores principales: Komine, Okiru, Hayashi, Keitaro, Natsume, Waka, Watanabe, Toshio, Seki, Youichi, Seki, Noriyasu, Yagi, Ryoji, Sukzuki, Wataru, Tamauchi, Hidekazu, Hozumi, Katsuto, Habu, Sonoko, Kubo, Masato, Satake, Masanobu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196077/
https://www.ncbi.nlm.nih.gov/pubmed/12835475
http://dx.doi.org/10.1084/jem.20021200

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