A Defect in Tryptophan Catabolism Impairs Tolerance in Nonobese Diabetic Mice

The predisposition of nonobese diabetic (NOD) mice to develop autoimmunity reflects deficiencies in both peripheral and central tolerance. Several defects have been described in these mice, among which aberrant antigen-presenting cell function and peroxynitrite formation. Prediabetes and diabetes in...

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Detalles Bibliográficos
Autores principales: Grohmann, Ursula, Fallarino, Francesca, Bianchi, Roberta, Orabona, Ciriana, Vacca, Carmine, Fioretti, Maria C., Puccetti, Paolo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196078/
https://www.ncbi.nlm.nih.gov/pubmed/12835483
http://dx.doi.org/10.1084/jem.20030633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196078/
https://www.ncbi.nlm.nih.gov/pubmed/12835483
http://dx.doi.org/10.1084/jem.20030633

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