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The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice
Programmed death-1 (PD-1) receptor, an inhibitory costimulatory molecule found on activated T cells, has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. We investigated the role of this pathway in the development of autoimmune diabetes. PD-1 or PD-L1...
Autores principales: | Ansari, Mohammed Javeed I., Salama, Alan D., Chitnis, Tanuja, Smith, R. Neal, Yagita, Hideo, Akiba, Hisaya, Yamazaki, Tomohide, Azuma, Miyuki, Iwai, Hideyuki, Khoury, Samia J., Auchincloss, Hugh, Sayegh, Mohamed H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196083/ https://www.ncbi.nlm.nih.gov/pubmed/12847137 http://dx.doi.org/10.1084/jem.20022125 |
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