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Bidirectional Interactions between Antigen-bearing Respiratory Tract Dendritic Cells (DCs) and T Cells Precede the Late Phase Reaction in Experimental Asthma: DC Activation Occurs in the Airway Mucosa but Not in the Lung Parenchyma

The airway mucosal response to allergen in asthma involves influx of activated T helper type 2 cells and eosinophils, transient airflow obstruction, and airways hyperresponsiveness (AHR). The mechanism(s) underlying transient T cell activation during this inflammatory response is unclear. We present...

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Detalles Bibliográficos
Autores principales: Huh, Joong C., Strickland, Deborah H., Jahnsen, Frode L., Turner, Debra J., Thomas, Jenny A., Napoli, Sylvia, Tobagus, Iriani, Stumbles, Philip A., Sly, Peter D., Holt, Patrick G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196086/
https://www.ncbi.nlm.nih.gov/pubmed/12835476
http://dx.doi.org/10.1084/jem.20021328

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