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CD80 Costimulation Is Essential for the Induction of Airway Eosinophilia

CD80 and CD86 (B7-1 and B7-2) are the ligands on antigen-presenting cells (APCs) which bind CD28 and deliver the costimulatory signals necessary for T cell activation. The reasons for the existence of two CD28 binding molecules are not well understood. We created a mutant version of CTLA4-Ig that co...

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Detalles Bibliográficos
Autores principales: Harris, Nicola, Peach, Robert, Naemura, Joe, Linsley, Peter S., Le Gros, Graham, Ronchese, Franca
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196101/
https://www.ncbi.nlm.nih.gov/pubmed/8996254