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Replacement of Pre-T Cell Receptor Signaling Functions by the CD4 Coreceptor
An important checkpoint in early thymocyte development ensures that only thymocytes with an in-frame T cell receptor for antigen β (TCR-β) gene rearrangement will continue to mature. Proper assembly of the TCR-β chain into the pre-TCR complex delivers signals through the src-family protein tyrosine...
Autores principales: | Norment, Anne M., Forbush, Katherine A., Nguyen, Nhan, Malissen, Marie, Perlmutter, Roger M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196103/ https://www.ncbi.nlm.nih.gov/pubmed/8996248 |
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