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The Chemokine SDF-1 Is a Chemoattractant for Human CD34(+) Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34(+) Progenitors to Peripheral Blood

Hematopoietic progenitor cells migrate in vitro and in vivo towards a gradient of the chemotactic factor stromal cell-derived factor-1 (SDF-1) produced by stromal cells. This is the first chemoattractant reported for human CD34(+) progenitor cells. Concentrations of SDF-1 that elicit chemotaxis also...

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Detalles Bibliográficos
Autores principales: Aiuti, A., Webb, I.J., Bleul, C., Springer, T., Gutierrez-Ramos, J.C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196104/
https://www.ncbi.nlm.nih.gov/pubmed/8996247