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The Chemokine SDF-1 Is a Chemoattractant for Human CD34(+) Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34(+) Progenitors to Peripheral Blood
Hematopoietic progenitor cells migrate in vitro and in vivo towards a gradient of the chemotactic factor stromal cell-derived factor-1 (SDF-1) produced by stromal cells. This is the first chemoattractant reported for human CD34(+) progenitor cells. Concentrations of SDF-1 that elicit chemotaxis also...
Autores principales: | Aiuti, A., Webb, I.J., Bleul, C., Springer, T., Gutierrez-Ramos, J.C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196104/ https://www.ncbi.nlm.nih.gov/pubmed/8996247 |
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