Cargando…
Developmental Regulation of VDJ Recombination By the Core Fragment of the T Cell Receptor α Enhancer
The role of T cell receptor α enhancer (E(α)) cis-acting elements in the developmental regulation of VDJ recombination at the TCR α/δ locus was examined in transgenic mice containing variants of a minilocus VDJ recombination substrate. We demonstrate that the 116-bp Tα1,2 core enhancer fragment of t...
Autores principales: | Roberts, Joseph L., Lauzurica, Pilar, Krangel, Michael S. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196107/ https://www.ncbi.nlm.nih.gov/pubmed/8996249 |
Ejemplares similares
-
Regulation of T Cell Receptor δ Gene Rearrangement by CBF/PEBP2
por: Lauzurica, Pilar, et al.
Publicado: (1997) -
VDJ Recombination: Artemis and Its In Vivo Role in Hairpin Opening
por: Mansilla-Soto, Jorge, et al.
Publicado: (2003) -
Individualized VDJ recombination predisposes the available Ig sequence space
por: Slabodkin, Andrei, et al.
Publicado: (2021) -
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development
por: Venigalla, Ram K C, et al.
Publicado: (2013) -
A Hands-On Activity to Demonstrate the Central Dogma of Molecular Biology Via a Simulated VDJ Recombination Activity
por: Marshall, Pamela A.
Publicado: (2017)